dextran

Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. IUPAC defines dextrans as "Branched poly-α-d-glucosides of microbial origin having glycosidic bonds predominantly C-1 → C-6". Dextran chains are of varying lengths (from 3 to 2000 kilodaltons). Dextran is a medication used in managing and treating various clinical conditions, including during hemorrhage, shock, surgical procedures, radiological imaging, antithrombotic administration, and ophthalmic relief of xerophthalmia. This activity reviews the indications, contraindications, adverse events, mechanisms of action, toxicity, and ... Dextran is a low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures. Dextran adalah salah satu bentuk zat besi berupa cairan obat. Hanya bisa didapatkan dengan resep dokter dan diberikan langsung oleh dokter; Manfaat dextran adalah untuk mengatasi anemia pada orang-orang yang kekurangan zat besi akibat efek samping pengobatan atau anemia yang belum terobati; Dextran Obat Apa? Untuk apa dextran digunakan? Dextran adalah salah satu bentuk zat besi yang berupa cairan obat. Zat besi adalah mineral yang penting untuk tubuh, berfungsi untuk membantu perpindahan oksigen di dalam darah. Obat ini tergolong obat resep, dan tidak bisa dibeli di apotek tanpa resep dokter. Dextran is a prescription medication used to treat hypovolemia (decreased volume of circulatory plasma blood) from surgery, trauma, or other causes. It is a volume expander that can be given by IV or injection. Learn about its warnings, side effects, dosage, interactions, and more. Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(1-6) linkages. The remaining a(1-3) linkages account for the branching of dextran. Conflicting data on the branch lengths implies that the average branch length is less than three glucose units. However, other methods indicate branches of greater than 50 glucose units exist. Dextran is an exopolysaccharide (EPS) synthesized by lactic acid bacteria (LAB) or their enzymes in the presence of sucrose. Dextran is composed of a linear chain of d-glucoses linked by α-(1→6) bonds, with possible branches of d-glucoses linked by α-(1→4), α-(1→3), or α-(1→2) bonds, which can be low (40 kDa) or high molecular weight (40 kDa). The characteristics of dextran in ... Indications and Dosage. Adult: Adjunctive therapy of shock due to burns, haemorrhage, surgery or other trauma: As 10% dextran 40 in 0.9% NaCl or 5% dextrose inj: Initially, 10 mL/kg via rapid infusion. Recommended Max: 20 mL/kg during the 1st 24 hours. If treatment continues beyond 24 hours, subsequent doses of up to 10 mL/kg daily may be given ... Dextran is widely exploited in medical products and as a component of drug-delivering nanoparticles (NPs). Here, we tested whether dextran can serve as the main substrate of NPs and form a stable backbone. We tested dextrans with several molecular masses under several synthesis conditions to optimize NP stability. The analysis of the obtained nanoparticles showed that dextran NPs that were ... Dextran sulfate has also shown to suppress the extravasation of lymphoblast in inflamed skin area, thereby exerting its anti-inflammatory effect. Dextran also helps in osmotically retaining the water in tissue that can contribute to the well-being and mechanical properties of the tissue concerned (Chen et al. 2020) . 10.5 Waste Water Management dextran from Leuconostoc mesenteroides NRRL B512, which allows controlling the molecular weights of the resulting dextrans [26,27]. 3. Characteristics of Dextran Dextran is a complex glucan formed by a main chain of D-glucoses linked by -(1 6) bonds with possible branches of D-glucoses with -(1 4), -(1 3), or -(1 2) bonds [28], as Dextran is a colloid consisting of glucose molecules which have been polymerized into chains to form high molecular weight polysaccharides.49 This compound is commercially available in a number of molecular sizes. Dextran, which has an average molecular weight of 40 000 Da, is referred to as low molecular weight dextran.